Production of hybrid oxytocin/vasopressin precursors and accumulation of oxytocin precursors in the rough endoplasmic reticulum of rat magnocellular neurons.

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Article

Production of hybrid oxytocin/vasopressin precursors and accumulation of oxytocin precursors in the rough endoplasmic reticulum of rat magnocellular neurons.

Advances in experimental medicine and biology - 1 Jan 1995

Morris J F, Pow D V, Mohr E, Richter D

Abstract excerpt

Most magnocellular hypothalamic neurons synthesize the precursor for either vasopressin (AVP) or oxytocin (OT). The AVP precursor is cleaved to give AVP, AVP-associated neurophysin (AVP-NP) and a glycopeptide (GP), whereas the OT precursor gives OT and OT-NP. In Brattleboro rats a frame-shift mut...

Topics

Aging
Animals
Arginine Vasopressin
Crossing Over, Genetic
Endoplasmic Reticulum, Rough
Hypothalamus
Mutation
Neurons
Oxytocin
Protein Precursors
Rats
Rats, Brattleboro

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Open in PubMed

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PMID: 8713951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8713951-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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