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Article

Mutant vasopressin precursor producing cells of the homozygous Brattleboro rat as a model for co-expression of neuropeptides.

Progress in brain research - 1 Jan 1992

van Leeuwen F W

Abstract excerpt

The homozygous Brattleboro rat (di/di) synthesizes a VP precursor with an abnormal C terminus, which is not transported from the rough endoplasmic reticulum to the Golgi apparatus. In addition, the phenotypic expression of co-existing peptides is differentially disturbed. Ang II and 7B2 are two of the peptides which are not detectable, whereas other peptides (e.g. galanin) are clearly expressed in mutant VP...

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PMID: 1302873
DOI: 10.1016/s0079-6123(08)61171-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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