A meta-analysis of the association of the deletion allele of the angiotensin-converting enzyme gene with myocardial infarction.

doi:10.1161/01.cir.94.4.708

Back to search

Article

A meta-analysis of the association of the deletion allele of the angiotensin-converting enzyme gene with myocardial infarction.

Circulation - 15 Aug 1996

Samani N J, Thompson J R, O'Toole L, Channer K, Woods K L

Abstract excerpt

BACKGROUND: The ACE gene is characterized by a polymorphism based on the presence (insertion [I]) or absence (deletion [D]) within intron 16 of a 287-basepair alu repeat sequence, resulting in three genotypes (DD and II homozygotes and ID heterozygotes). In 1992, the DD genotype was reported to b...

Topics

Genotype
Humans
Japan
Myocardial Infarction
Odds Ratio
Peptidyl-Dipeptidase A
Reference Values
Risk Factors
Sequence Deletion

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.