Article
The I allele of the angiotensin converting enzyme I/D polymorphism confers protection against coronary artery disease.
Coronary artery disease - 1 May 2010
Abchee Antoine, El-Sibai Mirvat, Youhanna Sonia, Yeretzian Joumana S, Estephan Hanine, Makhoul Nadine J, Puzantian Houry, Sawaya Jaber, Nasrallah Antoine, Rebeiz Abdallah G, Zreik Tony G, Azar Sami T, Zalloua Pierre A
Abstract excerpt
BACKGROUND: Mutations in genes regulating lipid metabolism, vasoactivity, and coagulation are important modulators of coronary artery disease (CAD). OBJECTIVE: This study investigated the association between allelic variants of the angiotensin converting enzyme (ACE), methytetrahydrofolate reductase, plasminogen activator inhibitor-1 and factor V genes and CAD. METHODS: Clinical, biochemical, and angiographic...
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