Article
Physical and transcript map of the minimally deleted region III on 17p implicated in the early development of Barrett's oesophageal adenocarcinoma.
Oncogene - 26 Jun 2003
Dunn Julie R, Risk Janet M, Langan Joanne E, Marlee Damian, Ellis Anthony, Campbell Fiona, Watson Alastair J M, Field John K
Abstract excerpt
Allelic imbalance (AI) studies on chromosome 17 (C17) in Barrett's oesophageal adenocarcinoma (BOA) tumours strongly suggest that a minimally deleted region on C17p harbours a BOA-associated gene with tumour suppressor function. This deleted region, designated minimal region III (MRIII), lies between the two microsatellite markers D17S1852 and D17S954. Computational sequence analysis techniques, BLAST and NIX,...
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