Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of Chromosome 18 in Neuroendocrine Tumors of the Small Intestine: The Enigma Remains

24 May 2016

Abstract excerpt

BACKGROUND/AIMS: Neuroendocrine tumors of the small intestine (SI-NETs) exhibit an increasing incidence and high mortality rate. Until now, no fundamental molecular event has been linked to the tumorigenesis and progression of these tumors. Only the loss of chromosome 18 (Chr18) has been shown in up to two thirds of SI-NETs, whereby the significance of this alteration is still not understood. We therefore...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gastrointestinal Tumor Research and Treatment
Share to Neuroendocrine Tumor Research Advances
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27222126
DOI: 10.1159/000446917

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of Chromosome 18 in Neuroendocrine Tumors of the Small Intestine: The Enigma RemainsPMID 27222126Read ↗

Genetics and epigenetics in small intestinal neuroendocrine tumours.Semantic proximity Read ↗

A single-cell transcriptomic comparison between small intestinal neuroendocrine tumors and their progenitorSemantic proximity Read ↗

Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumorsSemantic proximity Read ↗

Chromosome 18 deletions are common events in classical midgut carcinoid tumors.Semantic proximity Read ↗

Integrated genomic analysis of small intestinal neuroendocrine tumors provides further insights into molecular subgroups and identifies putative driver genesSemantic proximity Read ↗

The genomic landscape of small intestine neuroendocrine tumors.Semantic proximity Read ↗

Multiomic sequencing of paired primary and metastatic small bowel carcinoidsSemantic proximity Read ↗

SMAD4 haploinsufficiency in small intestinal neuroendocrine tumorsSemantic proximity Read ↗

Comparison of genetic alterations in neuroendocrine tumors: frequent loss of chromosome 18 in ileal carcinoid tumors.Semantic proximity Read ↗

SMAD4 haploinsufficiency in small intestinal neuroendocrine tumors.Semantic proximity Read ↗

Copy number alterations in small intestinal neuroendocrine tumors determined by array comparative genomic hybridizationSemantic proximity Read ↗

TCEB3C a putative tumor suppressor gene of small intestinal neuroendocrine tumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.