Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Physical and transcriptional mapping of the X-linked cleft palate and ankyloglossia (CPX) critical region.

Human genetics - 1 Jun 2001

Braybrook C, Warry G, Howell G, Mandryko V, Arnason A, Bjornsson A, Ross M T, Moore G E, Stanier P

Abstract excerpt

Cleft palate most commonly occurs as a sporadic multifactorial disorder with a clear but difficult to define genetic component. As a semi-dominant disorder, X-linked cleft palate (CPX) provides a useful model to investigate a congenital defect that is little influenced by non-genetic factors. By using an Icelandic kindred, CPX has been localised between DXS1196 and DXS1217 and mapped, in a 3-Mb yeast artificial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Artificial, Bacterial
Share to Chromosomes, Artificial, Yeast

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cleft Palate

Share to Contig Mapping

Share to Physical Chromosome Mapping

Share to Tissue Distribution

Share to Tongue

Source

Identifiers

PMID: 11499681
DOI: 10.1007/s004390100518

Genes

CPXCR1
KLHL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Physical and transcriptional mapping of the X-linked cleft palate and ankyloglossia (CPX) critical region.PMID 11499681Read ↗

Identification and characterization of KLHL4, a novel human homologue of the Drosophila Kelch gene that maps within the X-linked cleft palate and Ankyloglossia (CPX) critical region.Semantic proximity Read ↗

Localization of a mutant gene for cleft palate and ankyloglossia in an X-linked Icelandic family.Semantic proximity Read ↗

X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions.Semantic proximity Read ↗

TCEAL1 loss-of-function results in an X-linked dominant neurodevelopmental syndrome and drives the neurological disease trait in Xq22.2 deletions.Semantic proximity Read ↗

A 105 kb interstitial insertion in the Xq27.1 palindrome from pseudoautosomal region PAR1 causes a novel X-linked recessive compound phenotypeSemantic proximity Read ↗

Linkage analysis of X-linked cleft palate and ankyloglossia in Manitoba Mennonite and British Columbia Native kindreds.Semantic proximity Read ↗

Genomic organization of the human PEX gene mutated in X-linked dominant hypophosphatemic rickets.Semantic proximity Read ↗

Genome analysis and the human X chromosome.Semantic proximity Read ↗

Disruptions of the novel KIAA1202 gene are associated with X-linked mental retardation.Semantic proximity Read ↗

Medical sequencing of candidate genes for nonsyndromic cleft lip and palate.Semantic proximity Read ↗

Linkage of an X-chromosome cleft palate gene.Semantic proximity Read ↗

Mapping of the chicken cleft primary palate mutation on chromosome 11 and sequencing of the 4.9 Mb linked region.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.