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Article

Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation.

The Biochemical journal - 15 Oct 2003

Furuyama Tatsuo, Kitayama Kazuko, Yamashita Hitoshi, Mori Nozomu

Abstract excerpt

A forkhead-type transcription factor, DAF-16, is located in the most downstream part of the insulin signalling pathway via PI3K (phosphoinositide 3-kinase). It is essential for the extension of life-span and is also involved in dauer formation induced by food deprivation in Caenorhabditis elegans. In the present study, we addressed whether or not FOXO members AFX, FKHR (forkhead homologue in rhabdomyosarcoma) and...

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Source

Open in PubMed Open full text

Identifiers

PMID: 12820900
DOI: 10.1042/BJ20030022
PMCID: PMC1223677

Genes

PDK4
FOXO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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