Article
Linkage analysis of candidate loci for end-stage renal disease due to diabetic nephropathy.
Journal of the American Society of Nephrology : JASN - 1 Jul 2003
Iyengar Sudha K, Fox Katherine A, Schachere Marlene, Manzoor Fauzia, Slaughter Mary E, Covic Adrian M, Orloff S Mohammed, Hayden Patrick S, Olson Jane M, Schelling Jeffrey R, Sedor John R
Abstract excerpt
Diabetic nephropathy (DN), a major cause of ESRD, is undoubtedly multifactorial and is caused by environmental and genetic factors. To identify a genetic basis for DN susceptibility, we are collecting multiplex DN families in the Caucasian (CA) and African-American (AA) populations for whole genome scanning and candidate gene analysis. A candidate gene search of diabetic sibs discordantly affected, concordantly...
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