Article
Genomewide linkage scan for diabetic renal failure and albuminuria: the FIND study.
American journal of nephrology - 1 Jan 2011
Igo Robert P, Iyengar Sudha K, Nicholas Susanne B, Goddard Katrina A B, Langefeld Carl D, Hanson Robert L, Duggirala Ravindranath, Divers Jasmin, Abboud Hanna, Adler Sharon G, Arar Nedal H, Horvath Amanda, Elston Robert C, Bowden Donald W, Guo Xiuqing, Ipp Eli, Kao W H Linda, Kimmel Paul L, Knowler William C, Meoni Lucy A, Molineros Julio, Nelson Robert G, Pahl Madeline V, Parekh Rulan S, Rasooly Rebekah S, Schelling Jeffrey R, Shah Vallabh O, Smith Michael W, Winkler Cheryl A, Zager Philip G, Sedor John R, Freedman Barry I
Abstract excerpt
BACKGROUND: Diabetic nephropathy (DN) is a leading cause of mortality and morbidity in patients with type 1 and type 2 diabetes. The multicenter FIND consortium aims to identify genes for DN and its associated quantitative traits, e.g. the urine albumin:creatinine ratio (ACR). Herein, the results of whole-genome linkage analysis and a sparse association scan for ACR and a dichotomous DN phenotype are reported in...
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