Article
Linkage heterogeneity of end-stage renal disease on human chromosome 10.
Kidney international - 1 Sept 2002
Freedman Barry I, Rich Stephen S, Yu Hongrun, Roh Bong H, Bowden Donald W
Abstract excerpt
BACKGROUND: The human syntenic region of the rodent renal failure-1 gene (Rf1), an attractive candidate region for end-stage renal disease (ESRD) susceptibility, is located on chromosome 10q24-q26. In an attempt to assess for linkage between markers on human chromosome 10 and ESRD, we performed a linkage analysis in 356 African American sib pairs concordant for ESRD [199 sib pairs concordant for non-diabetic...
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