Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Flow cytometric technique for the detection of phagocytosed wear particles in patients with total joint arthroplasty.

Biomaterials - 1 Sept 2003

Niki Yasuo, Matsumoto Hideo, Otani Toshiro, Suda Yasunori, Yatabe Taku, Yoshimine Fumihiro, Kondo Makoto, Toyama Yoshiaki

Abstract excerpt

Wear particles from prosthetic implants have been shown to cause inflammatory synovitis and periprosthetic osteolysis. These particle-induced pathologies are manifestations of adverse cellular responses to phagocytosed particles. In this study, phagocytosis of polyethylene particles was analyzed using flow cytometry (FCM), and the clinical utility of FCM in diagnosing particle-induced synovitis was examined....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthroplasty, Replacement, Knee
Share to Fluorescein-5-isothiocyanate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipopolysaccharide Receptors

Share to Macrophages

Share to Monocytes

Share to Phagocytosis

Share to Receptors, IgG

Share to Synovitis

Source

Identifiers

PMID: 12818543
DOI: 10.1016/s0142-9612(03)00246-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Flow cytometric technique for the detection of phagocytosed wear particles in patients with total joint arthroplasty.PMID 12818543Read ↗

Phenotypic characteristics of joint fluid cells from patients with continuous joint effusion after total knee arthroplasty.Semantic proximity Read ↗

Five types of inflammatory arthritis following total knee arthroplasty.Semantic proximity Read ↗

Aseptic Loosening in Total Hip Arthroplasty: Pathophysiology, Biomarkers, and Preventive Treatment StrategiesSemantic proximity Read ↗

Phagocytosis of wear debris by osteoblasts affects differentiation and local factor production in a manner dependent on particle composition.Semantic proximity Read ↗

The characterisation of monocyte responses to mediators released from osteoarthritic and periprosthetic tissuesSemantic proximity Read ↗

Suppression of NF-κB-induced chronic inflammation mitigates inflammatory osteolysis in the murine continuous polyethylene particle infusion model.Semantic proximity Read ↗

Mutant monocyte chemoattractant protein 1 protein attenuates migration of and inflammatory cytokine release by macrophages exposed to orthopedic implant wear particles.Semantic proximity Read ↗

Mutant CCL2 protein coating mitigates wear particle-induced bone loss in a murine continuous polyethylene infusion model.Semantic proximity Read ↗

Autophagy inhibitors 3-MA and LY294002 repress osteoclastogenesis and titanium particle-stimulated osteolysisSemantic proximity Read ↗

Alternative macrophage activation in periprosthetic osteolysisSemantic proximity Read ↗

The parallels between particle induced lung overload and particle induced periprosthetic osteolysis (PPOL)Semantic proximity Read ↗

Titanium uptake, induction of RANK-L expression, and enhanced proliferation of human T-lymphocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.