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Article

Alternative macrophage activation in periprosthetic osteolysis

1 Jan 2008

Abstract excerpt

Several disorders characterized by macrophages accumulating non-disposable (or hard to dispose of) material or formation of multinucleated giant cell containing granulomas have been linked to elicitation of an alternative macrophage activation phenotype. Gene profiling efforts have shown that alternative macrophage activation can exist in numerous forms, each specific for the particular biological niche in which...

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PMID: 18365834
DOI: 10.1080/08916930701694626

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