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Article

The fourth blade within the beta-propeller is involved specifically in C3bi recognition by integrin alpha M beta 2.

The Journal of biological chemistry - 5 Sept 2003

Li Yang, Zhang Li

Abstract excerpt

Interactions between the complement degradation product C3bi and leukocyte integrin alpha M beta 2 are critical to phagocytosis of opsonized particles in host defense against foreign pathogens and certain malignant cells. Previous studies have mapped critical residues for C3bi binding to the I-domains of the alpha M and the beta2 subunits. However, the role of the alpha M beta-propeller in ligand binding remains...

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Identifiers

PMID: 12816955
DOI: 10.1074/jbc.M304190200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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