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Article

Isolated familial somatotropinomas: clinical and genetic considerations.

Transactions of the American Clinical and Climatological Association - 1 Jan 2003

Frohman Lawrence A

Abstract excerpt

The majority of somatotropinomas (GH-secreting pituitary adenomas) are sporadic, through a few occur with a familial aggregation, either as a component of multiple endocrine neoplasia, type 1 (MEN1) or Carney complex, or when unassociated with other tumors, as isolated familial somatotropinomas (IFS). The latter is a rare disorder associated with loss of heterozygosity (LOH) on chromosome 11q13, the locus of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12813918
PMCID: PMC2194520

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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