Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The dinB operon and spontaneous mutation in Escherichia coli.

Journal of bacteriology - 1 Jul 2003

McKenzie Gregory J, Magner Daniel B, Lee Peter L, Rosenberg Susan M

Abstract excerpt

Apparently conflicting data regarding the role of SOS-inducible, error-prone DNA polymerase IV (DinB) in spontaneous mutation are resolved by the finding that mutation is reduced by a polar allele with which dinB and neighboring yafN are deleted but not by two nonpolar dinB alleles. We demonstrate the existence of a dinB operon that contains four genes, dinB-yafN-yafO-yafP. The results imply a role for yafN,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Bacterial Proteins
Share to DNA Polymerase beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Escherichia coli Proteins

Share to Gene Expression Regulation, Bacterial

Share to Operon

Share to SOS Response, Genetics

Source

Open in PubMed Open full text

Identifiers

PMID: 12813093
DOI: 10.1128/JB.185.13.3972-3977.2003
PMCID: PMC161582

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The dinB operon and spontaneous mutation in Escherichia coli.PMID 12813093Read ↗

SOS mutator DNA polymerase IV functions in adaptive mutation and not adaptive amplification.Semantic proximity Read ↗

DinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coli.Semantic proximity Read ↗

Selection of dinB alleles suppressing survival loss upon dinB overexpression in Escherichia coli.Semantic proximity Read ↗

Escherichia coli YafP protein modulates DNA damaging property of the nitroaromatic compounds.Semantic proximity Read ↗

Selection-Enhanced Mutagenesis of lac Genes Is Due to Their Coamplification with dinB Encoding an Error-Prone DNA Polymerase.Semantic proximity Read ↗

What limits the efficiency of double-strand break-dependent stress-induced mutation in Escherichia coli?Semantic proximity Read ↗

A ΔdinB mutation that sensitizes Escherichia coli to the lethal effects of UV- and X-radiation.Semantic proximity Read ↗

A role for nonessential domain II of initiator protein, DnaA, in replication control.Semantic proximity Read ↗

Selection and Plasmid Transfer Underlie Adaptive Mutation in Escherichia coli.Semantic proximity Read ↗

Polymerases leave fingerprints: analysis of the mutational spectrum in Escherichia coli rpoB to assess the role of polymerase IV in spontaneous mutation.Semantic proximity Read ↗

Elevated expression of DNA polymerase II increases spontaneous mutagenesis in Escherichia coli.Semantic proximity Read ↗

Overproduction of Escherichia coli DNA polymerase DinB (Pol IV) inhibits replication fork progression and is lethal.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.