Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Mutations of MTHFR, MTR, MTRR genes as high risk factors for neural tube defects].

Medycyna wieku rozwojowego - 1 Jan 2000

Sliwerska Elzbieta, Szpecht-Potocka Agnieszka

Abstract excerpt

Neural tube defects (NTDs) have a polygenic background. There are numerous genes known to be high-risk genetic factors for NTDs. Ones of them are mutations of foliate metabolisms pathways genes. This paper shows the results of analysis of common mutations of MTHFR, MTR and MTRR genes. Results of screening mutations 2756A-->G and 66A-->G in MTR and MTRR genes respectively show that are might have an effect on NTDs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Alanine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cysteine

Share to Ferredoxin-NADP Reductase

Share to Glycine

Share to Neural Tube Defects

Share to Oxidoreductases Acting on CH-NH Group Donors

Share to Threonine

Source

Identifiers

PMID: 12810988

Genes

MTHFR
MTR
MTRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Mutations of MTHFR, MTR, MTRR genes as high risk factors for neural tube defects].PMID 12810988Read ↗

[Genetic risk factors of neural tube defects].Semantic proximity Read ↗

Analysis of MTR and MTRR Polymorphisms for Neural Tube Defects Risk Association.Semantic proximity Read ↗

"Polymorphisms in folate metabolism genes as maternal risk factor for neural tube defects: an updated meta-analysis".Semantic proximity Read ↗

[Methylene tetrahydrofolate reductase mutations as genetic risk factors for neural tube defects (NTF)].Semantic proximity Read ↗

Genetic variants in the folate pathway and the risk of neural tube defects: a meta-analysis of the published literature.Semantic proximity Read ↗

[Genes involved in folate metabolim and neural tube defects].Semantic proximity Read ↗

Association between the methionine synthase A2756G polymorphism and neural tube defect risk: a meta-analysis.Semantic proximity Read ↗

[Meta-analysis on relationship between the Chinese maternal MTHFR gene polymorphism(C677T) and neural tube defects in offspring].Semantic proximity Read ↗

[Meta analysis on the association between parental 5,10-methylenetetrahydrofolate reductase C677T polymorphism and the neural tube defects of their offspring].Semantic proximity Read ↗

Meta-analyses on the association of MTR A2756G and MTRR A66G polymorphisms with neural tube defect risks in Caucasian children.Semantic proximity Read ↗

Study on the relationship between genetic polymorphism of reductive folic acid carrier and the risk of neural tube defects.Semantic proximity Read ↗

Variants in MTHFR gene and neural tube defects susceptibility in China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.