Article
Rumpshaker: an X-linked mutation causing hypomyelination: developmental differences in myelination and glial cells between the optic nerve and spinal cord.
Glia - 1 Jan 1992
Fanarraga M L, Griffiths I R, McCulloch M C, Barrie J A, Kennedy P G, Brophy P J
Abstract excerpt
The X-linked mutation rumpshaker (rsh), which is probably an allele of jimpy (jp), causes hypomyelination in the CNS of mice. This study examines the developmental expression of the morphology, glial cells, and immunostaining of myelin proteins in the optic nerve and spinal cord. The optic nerve...
Topics
- Animals
- Demyelinating Diseases
- Female
- Glial Fibrillary Acidic Protein
- Immunohistochemistry
- Lipoproteins
- Mice
- Mice, Neurologic Mutants
- Mutation
- Myelin Basic Protein
- Neuroglia
- Oligodendroglia
- Optic Nerve
- Spinal Cord
- X Chromosome