Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular analysis of the association of HLA-B53 and resistance to severe malaria.

Nature - 3 Dec 1992

Hill A V, Elvin J, Willis A C, Aidoo M, Allsopp C E, Gotch F M, Gao X M, Takiguchi M, Greenwood B M, Townsend A R

Abstract excerpt

The protective association between the human leukocyte antigen HLA-B53 and severe malaria was investigated by sequencing of peptides eluted from this molecule followed by screening of candidate epitopes from pre-erythrocytic-stage antigens of Plasmodium falciparum in biochemical and cellular assays. Among malaria-immune Africans, HLA-B53-restricted cytotoxic T lymphocytes recognized a conserved nonamer peptide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to B-Lymphocytes
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Line

Share to Genetic Variation

Share to Molecular Sequence Data

Share to Oligodeoxyribonucleotides

Source

Identifiers

PMID: 1280333
DOI: 10.1038/360434a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular analysis of the association of HLA-B53 and resistance to severe malaria.PMID 1280333Read ↗

HLA-DQB1*0501-restricted Th1 type immune responses to Plasmodium falciparum liver stage antigen 1 protect against malaria anemia and reinfections.Semantic proximity Read ↗

HLA Alleles B*53:01 and C*06:02 Are Associated With Higher Risk of P. falciparum Parasitemia in a Cohort in Uganda.Semantic proximity Read ↗

Common West African HLA antigens are associated with protection from severe malariaSemantic proximity Read ↗

The HLA-B landscape of Africa: Signatures of pathogen-driven selection and molecular identification of candidate alleles to malaria protection.Semantic proximity Read ↗

Influence of age and HLA type on interferon-gamma (IFN-gamma) responses to a naturally occurring polymorphic epitope of Plasmodium falciparum liver stage antigen-1 (LSA-1).Semantic proximity Read ↗

Association of HLA alleles with Plasmodium falciparum severity in Malian children.Semantic proximity Read ↗

HLA-A2 supertype-restricted cell-mediated immunity by peripheral blood mononuclear cells derived from Malian children with severe or uncomplicated Plasmodium falciparum malaria and healthy controls.Semantic proximity Read ↗

HLA-DR-promiscuous T cell epitopes from Plasmodium falciparum pre-erythrocytic-stage antigens restricted by multiple HLA class II alleles.Semantic proximity Read ↗

Degenerate cytotoxic T cell epitopes from P. falciparum restricted by multiple HLA-A and HLA-B supertype alleles.Semantic proximity Read ↗

HLA alleles in relation to specific immunity to liver stage antigen-1 from plasmodium falciparum in Gabon.Semantic proximity Read ↗

MHC and malaria: the relationship between HLA class II alleles and immune responses to Plasmodium falciparum.Semantic proximity Read ↗

HLA-A*01-restricted cytotoxic T-lymphocyte epitope from the Plasmodium falciparum circumsporozoite protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.