Article
Kinetics of disappearance of resistance mutations and reappearance of wild-type during structured treatment interruptions.
AIDS (London, England) - 13 Jun 2003
Halfon Philippe, Durant Jacques, Clevenbergh Philippe, Carsenti Hélène, Celis Linda, Khiri Hacene, De Smet Koen, De Brauwer Annelies, Hulstaert Frank, Dellamonica Pierre
Abstract excerpt
OBJECTIVE: To monitor the disappearance of resistance-associated mutations and reappearance of wild-type (WT) virus during structured treatment interruptions (STI) using DNA sequencing and line probe assay. METHODS: Eleven HIV-1-infected patients participating in the MUTAVIR study undergoing a 3-month STI after multi-HAART failure were monitored biweekly. Genotypes were assessed by sequencing and VERSANT HIV-1...
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