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Article

No benefit of a structured treatment interruption based on genotypic resistance in heavily pretreated HIV-infected patients.

AIDS (London, England) - 14 Oct 2005

Ghosn Jade, Wirden Marc, Ktorza Nadine, Peytavin Gilles, Aït-Mohand Hocine, Schneider Luminita, Dominguez Stéphanie, Bricaire François, Calvez Vincent, Costagliola Dominique, Katlama Christine

Abstract excerpt

OBJECTIVE: To evaluate the potential benefits of a tailored antiretroviral treatment interruption with duration based on the observed reversion of resistance mutations. METHODS: In this open single-arm pilot study, 23 patients with multiple treatment failure interrupted therapy and underwent longitudinal genotypic resistance testing. Salvage gigatherapy was started when resistance mutations to at least two...

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Identifiers

PMID: 16184034
DOI: 10.1097/01.aids.0000181322.17679.b2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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