Mutations Related to Antiretroviral Resistance Identified by Ultra-Deep Sequencing in HIV-1 Infected Children under Structured Interruptions of HAART.

doi:10.1371/journal.pone.0147591

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Mutations Related to Antiretroviral Resistance Identified by Ultra-Deep Sequencing in HIV-1 Infected Children under Structured Interruptions of HAART.

PloS one - 1 Jan 2016

Vazquez-Guillen Jose Manuel, Palacios-Saucedo Gerardo C, Rivera-Morales Lydia G, Garcia-Campos Jorge, Ortiz-Lopez Rocio, Noguera-Julian Marc, Paredes Roger, Vielma-Ramirez Herlinda J, Ramirez Teresa J, Chavez-Garcia Marcelino, Lopez-Guillen Paulo, Briones-Lara Evangelina, Sanchez-Sanchez Luz M, Vazquez-Martinez Carlos A, Rodriguez-Padilla Cristina

Abstract excerpt

Although Structured Treatment Interruptions (STI) are currently not considered an alternative strategy for antiretroviral treatment, their true benefits and limitations have not been fully established. Some studies suggest the possibility of improving the quality of life of patients with this strategy; however, the information that has been obtained corresponds mostly to studies conducted in adults, with a lack...

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PMID: 26807922
DOI: 10.1371/journal.pone.0147591
PMCID: PMC4725846

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