Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A study of host defence peptide beta-defensin 3 in primates.

The Biochemical journal - 15 Sept 2003

Boniotto Michele, Antcheva Nikolinka, Zelezetsky Igor, Tossi Alessandro, Palumbo Valeria, Verga Falzacappa Maria Vittoria, Sgubin Silvia, Braida Laura, Amoroso Antonio, Crovella Sergio

Abstract excerpt

We have investigated the molecular evolution of the gene coding for beta-defensin 3 (DEFB103) in 17 primate species including humans. Unlike the DEFB4 genes (coding for beta-defensin 2) [Boniotto, Tossi, Del Pero, Sgubin, Antcheva, Santon and Masters (2003) Genes Immun. 4, 251-257], DEFB103 shows a marked degree of conservation in humans, Great Apes and New and Old World monkeys. Only the Hylobates concolor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Amino Acid Substitution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Base Sequence

Share to beta-Defensins

Share to Gorilla gorilla

Share to Pan troglodytes

Share to Pongo pygmaeus

Share to Primates

Source

Open in PubMed Open full text

Identifiers

PMID: 12795637
DOI: 10.1042/BJ20030528
PMCID: PMC1223632

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A study of host defence peptide beta-defensin 3 in primates.PMID 12795637Read ↗

Histatins in non-human primates: gene variations and functional effects.Semantic proximity Read ↗

Human beta-defensin 1: a restless warrior against allergies, infections and cancer.Semantic proximity Read ↗

Beta-defensin 1 gene variability among non-human primates.Semantic proximity Read ↗

Molecular and functional analysis of human β-defensin 3 action at melanocortin receptors.Semantic proximity Read ↗

The complexity of selection at the major primate beta-defensin locus.Semantic proximity Read ↗

Human defensin 5 disulfide array mutants: disulfide bond deletion attenuates antibacterial activity against Staphylococcus aureus.Semantic proximity Read ↗

Functional determinants of human enteric α-defensin HD5: crucial role for hydrophobicity at dimer interface.Semantic proximity Read ↗

Directional and balancing selection in human beta-defensins.Semantic proximity Read ↗

Evolution of the primate cathelicidin. Correlation between structural variations and antimicrobial activity.Semantic proximity Read ↗

Activity, Expression and Genetic Variation of Canine β-Defensin 103: A Multifunctional Antimicrobial Peptide in the Skin of Domestic DogsSemantic proximity Read ↗

Homology modeling and molecular dynamics of β-defensin II variants in Amazonian sheep.Semantic proximity Read ↗

Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.