Article
Homology modeling and molecular dynamics of β-defensin II variants in Amazonian sheep.
Genetics and molecular research : GMR - 29 Jan 2016
Siqueira A S, de Souza B B, Lima A R J, Barbosa E M, Azevedo J S N, Gonçalves E C, Silva Filho E
Abstract excerpt
β-defensins are capable of creating pores in the bacterial membrane. In this study, we aim to determine the structure of 3 different sheep β-defensin 2 (SBD-2) sequences by molecular modeling. A herd of 47 sheep from the Centre for Ovine and Caprine Research of Pará was selected for this investigation. The AA, AG, and GG alleles were found on β-defensin sequences. We used homology modeling and molecular dynamic...
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