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Article

Dynamic Changes in Gene Expression During Human Trophoblast Differentiation

1 Jan 2003

Abstract excerpt

The genetic program that directs human placental differentiation is poorly understood. In a recent study, we used DNA microarray analyses to determine genes that are dynamically regulated during human placental development in an in vitro model system in which highly purified cytotrophoblast cells aggregate spontaneously and fuse to form a multinucleated syncytium that expresses placental lactogen, human chorionic...

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PMID: 12795423
DOI: 10.1210/rp.58.1.263

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