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Transcriptomic Signature of Trophoblast Differentiation in a Human Embryonic Stem Cell Model1

3 Mar 2011

Abstract excerpt

Identification of genes involved in trophoblast differentiation is of great interest in understanding cellular and molecular mechanisms involved in placental development and is relevant clinically to fetal development, fertility, and maternal health. Herein, we investigated differentiation of human embryonic stem cells (hESCs) down the trophoblast lineage by culture with bone morphogenetic protein 4 (BMP4) over a...

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PMID: 21368299
DOI: 10.1095/biolreprod.110.086413

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