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Trophoblast Differentiation Affects Crucial Nutritive Functions of Placental Membrane Transporters

22 Feb 2022

Abstract excerpt

Cytotrophoblasts are progenitor cells that proliferate and fuse to form the multinucleated syncytiotrophoblast layer, implicated in placental endocrine and transport functions. While membrane transporters play a critical role in the distribution of nutrients, hormones, and xenobiotics at the maternal-fetal interface, their selectivity to the syncytiotrophoblast layer is poorly characterized. We aimed to evaluate...

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PMID: 35273963
DOI: 10.3389/fcell.2022.820286

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