Article
Paired-like repression/activation in pituitary development.
Recent progress in hormone research - 1 Jan 2003
Olson Lorin E, Dasen Jeremy S, Ju Bong Gun, Tollkuhn Jessica, Rosenfeld Michael G
Abstract excerpt
Pituitary gland development is controlled by signals that guide expression of specific combinations of transcription factors that dictate serial determination and differentiation events. One class of factors is paired-like homeodomain factors. Two that have been investigated are the repressor Hex1/Rpx and activator prophet of Pit-1 (Prop-1), which exert selective roles during pituitary development. The opposing...
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