Article
The role of transcription factors implicated in anterior pituitary development in the aetiology of congenital hypopituitarism.
Annals of medicine - 1 Jan 2006
Kelberman Daniel, Dattani Mehul T
Abstract excerpt
The anterior pituitary gland is a central regulator of growth, reproduction and homeostasis, and is the end-product of a carefully orchestrated pattern of expression of signalling molecules and transcription factors leading to the development of this complex organ secreting six hormones from five different cell types. Naturally occurring and transgenic murine models have demonstrated a role for many of these...
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