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Article

A region of allelic imbalance in 1q31-32 in primary breast cancer coincides with a recombination hot spot.

Cancer research - 1 Oct 1997

Benítez J, Osorio A, Barroso A, Arranz E, Díaz-Guillén M A, Robledo M, Rodríguez de Córdoba S, Heine-Suñer D

Abstract excerpt

Previous studies have shown that the 1q31-32 region frequently presents allelic imbalance (AI) in various neoplastic diseases, such as breast cancer, medulloblastoma, male germ cell tumors, and renal collecting duct carcinoma, suggesting the presence of a tumor suppressor gene in this location. We used 19 informative microsatellite markers to analyze 33 primary breast tumors for AI in the 1q31-32 region. Our...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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PMID: 9331079

Genes

REN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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