Article
Breast cell invasive potential relates to the myoepithelial phenotype.
International journal of cancer - 10 Aug 2003
Gordon Linda A, Mulligan Kellie T, Maxwell-Jones Helen, Adams Matthew, Walker Rosemary A, Jones J Louise
Abstract excerpt
On the basis of marker profile, the majority of breast carcinomas are thought to be derived from luminal epithelial cells; however, a subgroup of tumours with more mesenchymal characteristics are associated with a worse prognosis. The hypothesis of our study is that some breast carcinomas exhibit myoepithelial rather than pure mesenchymal differentiation and that acquisition of myoepithelial characteristics...
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