Article
An epithelial to mesenchymal transition programme does not usually drive the phenotype of invasive lobular carcinomas.
The Journal of pathology - 1 Mar 2016
McCart Reed Amy E, Kutasovic Jamie R, Vargas Ana C, Jayanthan Janani, Al-Murrani Amel, Reid Lynne E, Chambers Rachael, Da Silva Leonard, Melville Lewis, Evans Elizabeth, Porter Alan, Papadimos David, Thompson Erik W, Lakhani Sunil R, Simpson Peter T
Abstract excerpt
Epithelial to mesenchymal transition (EMT) is a cellular phenotype switching phenomenon which occurs during normal development and is proposed to promote tumour cell invasive capabilities during tumour progression. Invasive lobular carcinoma (ILC) is a histological special type of breast cancer with a peculiar aetiology - the tumour cells display an invasive growth pattern, with detached, single cells or single...
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