Article
Cytometric and biochemical characterization of human breast cancer cells reveals heterogeneous myoepithelial phenotypes.
Cytometry. Part A : the journal of the International Society for Analytical Cytology - 1 Nov 2012
Leccia Felicia, Nardone Agostina, Corvigno Sara, Vecchio Luigi Del, De Placido Sabino, Salvatore Francesco, Veneziani Bianca Maria
Abstract excerpt
To determine whether cell cultures maintain the cellular heterogeneity of primary tissues and may therefore be used for in vitro modeling of breast cancer subtypes, we evaluated the expression of a cell surface marker panel in breast cancer cell cultures derived from various subtypes of human breast carcinoma. We used a four-color flow cytometry strategy to immunophenotype seven human breast cancer cell cultures...
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