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Article

Inactivation of the RASSF1A in osteosarcoma.

Oncology reports - 1 Jan 2000

Lim Sungjig, Yang Moon Ho, Park Jae Hoon, Nojima Takayuki, Hashimoto Hiroshi, Unni K Krishnan, Park Yong-Koo

Abstract excerpt

We investigated the expression and mutation of three isoforms of the Ras effector RASSF1 in 10 primary osteosarcomas and 6 osteosarcoma cell lines. RASSF1A was not expressed in 40% (4/10) of the primary osteosarcomas and 83.3% (5/6) of the osteosarcoma cell lines. RASSF1B and RASSF1C expression was absent in 30% (3/10) and 0% (0/10) of primary tumors, and 100% (6/6) and 0% (0/6) of osteosarcoma cell lines,...

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Source

Identifiers

PMID: 12792742

Genes

RASSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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