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Article

Genetic modification of risk assessment based on staging of preclinical type 1 diabetes in siblings of affected children.

The Journal of clinical endocrinology and metabolism - 1 Jun 2003

Mrena S, Savola K, Kulmala P, Reijonen H, Ilonen J, Akerblom H K, Knip M

Abstract excerpt

We set out to study the association between human leukocyte antigen-defined genetic disease susceptibility and the stage of preclinical type 1 diabetes and whether genetic predisposition affects the natural course of preclinical diabetes in initially nondiabetic siblings of affected children. A total of 701 initially unaffected siblings were graded into four stages of preclinical type 1 diabetes based on the...

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Identifiers

PMID: 12788873
DOI: 10.1210/jc.2002-020644

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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