Article
Disease-associated autoantibodies as predictive markers of type 1 diabetes mellitus in siblings of affected children.
Journal of pediatric endocrinology & metabolism : JPEM - 1 Jan 2001
Kimpimäki T, Knip M
Abstract excerpt
The long latent preclinical period of type 1 diabetes mellitus (DM) makes it possible to identify individuals at increased risk for clinical DM before the beta-cell destructive process has reached the point of no return. A series of reports on the predictive value of DM-associated autoantibodies are available in first-degree relatives of patients with type 1 DM, but only a few of these studies target exclusively...
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