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Article

Association between tuberculosis and a polymorphic NFkappaB binding site in the interferon gamma gene.

Lancet (London, England) - 31 May 2003

Rossouw Manda, Nel Hendrik J, Cooke Graham S, van Helden Paul D, Hoal Eileen G

Abstract excerpt

Interferon gamma is believed to be crucial for host defence against many infections. To test the hypothesis that a polymorphism in the gene for interferon gamma (IFNG) is associated with susceptibility to tuberculosis, we did two independent investigations. In a case-control study of 313 tuberculosis cases, we noted a significant association between a polymorphism (+874A-->T) in IFNG and tuberculosis in a South...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12788577
DOI: 10.1016/S0140-6736(03)13491-5

Genes

IFNG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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