Article
Interferon-gamma gene+874T-A polymorphism is associated with tuberculosis and gamma interferon response.
Tuberculosis (Edinburgh, Scotland) - 1 May 2007
Sallakci Nilgün, Coskun Mesut, Berber Zafer, Gürkan Fuat, Kocamaz Halil, Uysal Gülnar, Bhuju Sabin, Yavuzer Ugur, Singh Mahavir, Yeğin Olcay
Abstract excerpt
Interferon-gamma is the most important cytokine in resistance to mycobacterial diseases and common variants of interferon-gamma gene could be related to tuberculosis susceptibility. We tested the hypothesis that the interferon-gamma+874T-A polymorphism is associated with tuberculosis disease, and affects the interferon-gamma response. We determined by pyrosequencing the distribution of the interferon-gamma+874T-A...
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