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Article

Role of IFN-gamma +874 T/A single nucleotide polymorphism in the tuberculosis outcome among Brazilians subjects.

Molecular biology reports - 1 Dec 2008

Amim Lucia H L V, Pacheco Antonio G, Fonseca-Costa Joseane, Loredo Carla S, Rabahi Marcelo F, Melo Maria H, Ribeiro Fernando C V, Mello Fernanda C Q, Oliveira Martha M, Lapa e Silva José R, Ottenhoff Tom H, Kritski Afrânio L, Santos Adalberto R

Abstract excerpt

Several genetic cytokine gene variants have been associated with host susceptibility to infectious diseases, including tuberculosis. Based upon the importance of IFN-gamma in protective immunity against Mycobacterium tuberculosis, and the functional role of the IFN-gamma + 874T/A single nucleotide polymorphism in IFN-gamma production, we genotyped 93 Brazilian tuberculosis patients and 266 asymptomatic health...

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Identifiers

PMID: 17682837
DOI: 10.1007/s11033-007-9123-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Role of IFN-gamma +874 T/A single nucleotide polymorphism in the tuberculosis outcome among Brazilians subjects.PMID 17682837Read ↗

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Interferon-gamma gene+874T-A polymorphism is associated with tuberculosis and gamma interferon response.Semantic proximity Read ↗

A single nucleotide polymorphism in the interferon-γ gene (IFNG +874 T/A) is associated with susceptibility to tuberculosisSemantic proximity Read ↗

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