Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of eight genes modulating interferon gamma and human genetic susceptibility to tuberculosis: a case-control association study.

BMC infectious diseases - 7 Jun 2010

Möller Marlo, Nebel Almut, van Helden Paul D, Schreiber Stefan, Hoal Eileen G

Abstract excerpt

BACKGROUND: Interferon gamma is a major macrophage-activating cytokine during infection with Mycobacterium tuberculosis, the causative pathogen of tuberculosis, and its role has been well established in animal models and in humans. This cytokine is produced by activated T helper 1 cells, which can best deal with intracellular pathogens such as M. tuberculosis. Based on the hypothesis that genes which regulate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Interferon-gamma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mycobacterium tuberculosis

Share to Polymorphism, Genetic

Share to South Africa

Share to Tuberculosis

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 20525402
DOI: 10.1186/1471-2334-10-154
PMCID: PMC2891757

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of eight genes modulating interferon gamma and human genetic susceptibility to tuberculosis: a case-control association study.PMID 20525402Read ↗

Polymorphism within the interferon-gamma/receptor complex is associated with pulmonary tuberculosis.Semantic proximity Read ↗

Association between tuberculosis and a polymorphic NFkappaB binding site in the interferon gamma gene.Semantic proximity Read ↗

Association between interferon-gamma (IFN-γ) gene polymorphisms and tuberculosis susceptibility: a systematic review and meta-analysis.Semantic proximity Read ↗

Association study of polymorphisms in interferon-γ receptor genes with the risk of pulmonary tuberculosis.Semantic proximity Read ↗

Polymorphism in the interferon-gamma receptor-1 gene and susceptibility to pulmonary tuberculosis in The Gambia.Semantic proximity Read ↗

Gene polymorphisms in patients with pulmonary tuberculosis from Mozambique.Semantic proximity Read ↗

Association study of genes controlling IL-12-dependent IFN-γ immunity: STAT4 alleles increase risk of pulmonary tuberculosis in Morocco.Semantic proximity Read ↗

Genetic Polymorphism of Tumor Necrosis Factor-Alpha, Interferon-Gamma and Interleukin-10 and Association With Risk of Mycobacterium Tuberculosis Infection.Semantic proximity Read ↗

Human genetic susceptibility to tuberculosis.Semantic proximity Read ↗

IFNG +874T/A, IL10 -1082G/A and TNF -308G/A polymorphisms in association with tuberculosis susceptibility: a meta-analysis study.Semantic proximity Read ↗

A single nucleotide polymorphism in the interferon-γ gene (IFNG +874 T/A) is associated with susceptibility to tuberculosisSemantic proximity Read ↗

Footprints of genetic susceptibility to pulmonary tuberculosis: cytokine gene variants in north Indians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.