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Determinants within the C-terminus of the human norepinephrine transporter dictate transporter trafficking, stability, and activity.

Archives of biochemistry and biophysics - 1 Aug 2002

Bauman Patricia A, Blakely Randy D

Abstract excerpt

The function of the human norepinephrine transporter (hNET) depends on its presence at the cell surface. A role for the hNET C-terminus in trafficking the transporter to the surface has been suggested by the report of a bovine NET C-terminal splice variant that accumulates within heterologous host cells, and a human variant homolog has also been reported. We examined the relevance of the C-terminus of hNET to...

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PMID: 12127072
DOI: 10.1016/s0003-9861(02)00232-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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