Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Maternal alleles acquiring paternal methylation patterns in biparental complete hydatidiform moles.

Human molecular genetics - 15 Jun 2003

El-Maarri Osman, Seoud Muhieddine, Coullin Philippe, Herbiniaux Ursula, Oldenburg Johannes, Rouleau Guy, Slim Rima

Abstract excerpt

We previously mapped a maternal locus responsible for biparental complete hydatidiform moles (BiCHMs) to 19q13.4. The two index patients had a total of 14 molar pregnancies, eight abortions at various developmental stages, and one 16-year-old healthy offspring. We suggested that the defective gene deregulates the expression of imprinted genes. Here, we report the methylation status of four imprinted genes in two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromogranins
Share to Chromosomes, Human, Pair 19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Protein alpha Subunits, Gs

Share to Hydatidiform Mole

Share to Ribonucleoproteins, Small Nuclear

Share to RNA, Untranslated

Share to snRNP Core Proteins

Share to Sulfites

Source

Identifiers

PMID: 12783848
DOI: 10.1093/hmg/ddg152

Genes

SNRPN
PEG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Maternal alleles acquiring paternal methylation patterns in biparental complete hydatidiform moles.PMID 12783848Read ↗

Patients with familial biparental hydatidiform moles have normal methylation at imprinted genes.Semantic proximity Read ↗

Biparental hydatidiform moles: a maternal effect mutation affecting imprinting in the offspring.Semantic proximity Read ↗

The human homologue (PEG3) of the mouse paternally expressed gene 3 (Peg3) is maternally imprinted but not mutated in women with familial recurrent hydatidiform molar pregnancies.Semantic proximity Read ↗

Hydatidiform mole and triploidy: the role of genomic imprinting in placental developmentSemantic proximity Read ↗

Genetic Mapping of a Maternal Locus Responsible for Familial Hydatidiform MolesSemantic proximity Read ↗

Familial hydatidiform molar pregnancy: the germline imprinting defect hypothesis?Semantic proximity Read ↗

Familial molar tissues due to mutations in the inflammatory gene, NALP7, have normal postzygotic DNA methylation.Semantic proximity Read ↗

Absence of Maternal Methylation in Biparental Hydatidiform Moles from Women with NLRP7 Maternal-Effect Mutations Reveals Widespread Placenta-Specific Imprinting.Semantic proximity Read ↗

Bovine SNRPN Methylation Imprint in Oocytes and Day 17 In Vitro-Produced and Somatic Cell Nuclear Transfer Embryos1Semantic proximity Read ↗

Genetic refinement and physical mapping of a biparental complete hydatidiform mole locus on chromosome 19q13.4.Semantic proximity Read ↗

Evidence of a genetic heterogeneity of familial hydatidiform moles.Semantic proximity Read ↗

Genetic and epigenetic analysis of recurrent hydatidiform mole.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.