Article
Evidence of a genetic heterogeneity of familial hydatidiform moles.
Placenta - 1 Jan 2005
Slim R, Fallahian M, Rivière J-B, Zali M R
Abstract excerpt
We previously mapped a maternal recessive locus responsible for familial hydatidiform moles (HMs) to 19q13.4. The candidate region has recently been narrowed down to 1.1 megabases. Here, we report the segregation of alleles at 18 genetic markers, including nine new ones, from the HMs candidate region in a recently reported consanguineous family. In this family, five affected women had a total of seven HMs, three...
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