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Article

Regular exercise is beneficial to a mouse model of amyotrophic lateral sclerosis

27 May 2003

Abstract excerpt

We tested whether a regular exercise regimen was associated with a change in the life span of G93A-SOD1 transgenic mice, a model of familial ALS. Regular treadmill running for 10 weeks led to a significant increase in the life span of G93A-SOD1 mice. The effect was stronger in male mice, whereas there was only a trend between exercised and sedentary female G93A-SOD1 mice. The data suggest that regular exercise...

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PMID: 12783429
DOI: 10.1002/ana.10597

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