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Article

Human arteries engineered in vitro.

EMBO reports - 1 Jun 2003

McKee J Andrew, Banik Soma S R, Boyer Matthew J, Hamad Nesrin M, Lawson Jeffrey H, Niklason Laura E, Counter Christopher M

Abstract excerpt

There is a pressing need to develop methods to engineer small-calibre arteries for bypass surgery. We hypothesized that the rate-limiting step that has thwarted previous attempts to engineer such vessels from non-neonatal tissues is the limited proliferative capacity of smooth muscle cells (SMCs), which are the main cellular component of these vessels. Ectopic expression of the human telomerase reverse...

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Share to Aorta
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelium, Vascular

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Source

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Identifiers

PMID: 12776184
DOI: 10.1038/sj.embor.embor847
PMCID: PMC1319197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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