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Article

Human Endothelial Cell Life Extension by Telomerase Expression

1 Sept 1999

Abstract excerpt

Normal human endothelial cells, like other somatic cells in culture, divide a limited number of times before entering a nondividing state called replicative senescence. Expression of the catalytic component of human telomerase, human telomerase reverse transcriptase (hTERT), extends the life span of human fibroblasts and retinal pigment epithelial cells beyond senescence without causing neoplastic transformation...

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Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Share to Retinoids in leukemia and cellular processes
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Identifiers

PMID: 10473565
DOI: 10.1074/jbc.274.37.26141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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