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Article

Endoglin is not a major susceptibility gene for intracranial aneurysm among Japanese.

Stroke - 1 Jul 2003

Onda Hideaki, Kasuya Hidetoshi, Yoneyama Taku, Hori Tomokatsu, Nakajima Toshiaki, Inoue Ituro

Abstract excerpt

BACKGROUND AND PURPOSE: A 6-base insertion (6bINS) polymorphism in intron 7 of the endoglin gene (ENG), which codes for a component of the transforming growth factor-beta receptor complex, was reported to be associated with intracranial aneurysm (IA) in a Japanese population. A recent report using a white population could not replicate the association. We tested for this association with high statistical power in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12775886
DOI: 10.1161/01.STR.0000075770.70554.99

Genes

ENG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Endoglin is not a major susceptibility gene for intracranial aneurysm among Japanese.PMID 12775886Read ↗

Lack of association between endoglin intron 7 insertion polymorphism and intracranial aneurysms in a white population: evidence of racial/ethnic differences.Semantic proximity Read ↗

A polymorphic variant of the endoglin gene is associated with increased risk for intracranial aneurysms in a Korean population.Semantic proximity Read ↗

A DNA sequence polymorphism in the endoglin gene is not associated with intracranial aneurysm or aneurysmal subarachnoid hemorrhage.Semantic proximity Read ↗

Genomewide-linkage and haplotype-association studies map intracranial aneurysm to chromosome 7q11.Semantic proximity Read ↗

Role of Endoglin Insertion and rs1800956 Polymorphisms in Intracranial Aneurysm Susceptibility: A Meta-Analysis.Semantic proximity Read ↗

Absence of linkage of familial intracranial aneurysms to 7q11 in highly aggregated Japanese families.Semantic proximity Read ↗

Extended single nucleotide polymorphism and haplotype analysis of the elastin gene in Caucasians with intracranial aneurysms provides evidence for racially/ethnically based differences.Semantic proximity Read ↗

Confirmation of chromosome 7q11 locus for predisposition to intracranial aneurysm.Semantic proximity Read ↗

Elastin polymorphism haplotype and intracranial aneurysms are not associated in Central Europe.Semantic proximity Read ↗

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Association analysis of common variants of ELN, NOS2A, APOE and ACE2 to intracranial aneurysm.Semantic proximity Read ↗

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