Article
A polymorphic variant of the endoglin gene is associated with increased risk for intracranial aneurysms in a Korean population.
Surgical neurology - 1 Jul 2008
Joo Sung-Pil, Lee Jung-Kil, Kim Tae-Sun, Kim Myeong-Kyu, Lee Il-Kwon, Seo Bo-Ra, Kim Jae-Hyoo, Kim Soo-Han, Oh Chang-Wan
Abstract excerpt
BACKGROUND: Endoglin is a component of the transforming growth factor-beta receptor complex and is predominantly expressed on the cell surface of endothelial cells. It plays an important role in vascular growth and development. There have been conflicting reports on whether a polymorphic variant, in the endoglin gene, is associated with risk for IAs. In this study, we investigated whether polymorphisms of the...
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