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Article

Absence of linkage of familial intracranial aneurysms to 7q11 in highly aggregated Japanese families.

Stroke - 1 Apr 2003

Yamada Shigeki, Utsunomiya Maki, Inoue Kayoko, Nozaki Kazuhiko, Miyamoto Susumu, Hashimoto Nobuo, Takenaka Katsunobu, Yoshinaga Takeo, Koizumi Akio

Abstract excerpt

BACKGROUND AND PURPOSE: We sought to test the linkage of familial intracranial aneurysms (FIAs) to the ELN (elastin) locus in chromosome 7q11 reported previously. METHODS: Intracranial aneurysm (IA) probands were searched from patient records or neurosurgeons' recalls in collaborating hospitals. Members of the participating probands' families who had unknown affection status were screened by MR angiography and...

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Share to Chromosomes, Human, Pair 7
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12649519
DOI: 10.1161/01.STR.0000062887.71400.B4

Genes

ELN
NPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

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Absence of linkage of familial intracranial aneurysms to 7q11 in highly aggregated Japanese families.PMID 12649519Read ↗

Genomewide-linkage and haplotype-association studies map intracranial aneurysm to chromosome 7q11.Semantic proximity Read ↗

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Molecular genetic analysis of two large kindreds with intracranial aneurysms demonstrates linkage to 11q24-25 and 14q23-31.Semantic proximity Read ↗

Genome screen in familial intracranial aneurysm.Semantic proximity Read ↗

Elastin polymorphism haplotype and intracranial aneurysms are not associated in Central Europe.Semantic proximity Read ↗

A haplotype spanning two genes, ELN and LIMK1, decreases their transcripts and confers susceptibility to intracranial aneurysms.Semantic proximity Read ↗

Genomewide linkage in a large Caucasian family maps a new locus for intracranial aneurysms to chromosome 13q.Semantic proximity Read ↗

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