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Article

Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos.

Molecular and cellular biology - 1 Jun 2003

Stenvers Kaye L, Tursky Melinda L, Harder Kenneth W, Kountouri Nicole, Amatayakul-Chantler Supavadee, Grail Dianne, Small Clayton, Weinberg Robert A, Sizeland Andrew M, Zhu Hong-Jian

Abstract excerpt

The type III transforming growth factor beta (TGFbeta) receptor (TbetaRIII) binds both TGFbeta and inhibin with high affinity and modulates the association of these ligands with their signaling receptors. However, the significance of TbetaRIII signaling in vivo is not known. In this study, we have sought to determine the role of TbetaRIII during development. We identified the predominant expression sites of...

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Identifiers

PMID: 12773577
DOI: 10.1128/MCB.23.12.4371-4385.2003
PMCID: PMC156130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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